BCL-XL is essential for the protection from secondary anemia caused by radiation-induced fatal kidney damage
K. Brinkmann, P. Waring, S. Glaser, V. Wimmer, D. Nhu, L. Whitehead, A. R. Delbridge, G. Lessene, M. Herold, G. L. Kelly, S. Grabow, A. Strasser
The paper shows that BCL-XL protects adult kidneys from radiation-induced damage, leading to secondary anemia, and highlights its importance in cancer therapy combinations.
bioRxiv · Apr 28, 2020 · PreprintPharmacology & Toxicology