Author

V. Wimmer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. J. Kueh· 2 shared A. Strasser· 2 shared K. Brinkmann· 2 shared P. Bouillet· 2 shared A. K. Voss· 1 shared A. R. Delbridge· 1 shared A. Tee· 1 shared B. C. Duckworth· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

A. J. Kueh

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transient inhibition of type I interferon enhances CD8+ T cell stemness and vaccine protection

B. J. Broomfield, C. W. Tan, R. Z. Qin, B. C. Duckworth, C. Alvarado, L. Dalit, J. Chen, L. Mackiewicz, H. Muramatsu, M. Pellegrini, K. Rogers, W. J. Moon, S. L. Nutt, M. J. Davis, N. Pardi, , J. R. Groom

This paper shows that temporarily blocking type I interferon during viral infection boosts CD8+ T cell memory and vaccine effectiveness by promoting TSCM cell formation.

bioRxiv · Jun 26, 2024Immunology

Relative importance of MCL-1's Anti-Apoptotic versus Non-Apoptotic Functions in vivo

K. Brinkmann, K. McArthur, A. Tee, A. J. Kueh, S. Malelang, V. Wimmer, L. Gibson, C. L. Rowe, P. Arandjelovic, G. Dewson, T. Putoczki, P. Bouillet, N. Fu, T. Thomas, M. J. Herold, , A. Strasser

This study replaces MCL-1 with other anti-apoptotic proteins in mice to determine the relative importance of MCL-1's anti-apoptotic versus non-apoptotic functions in development and physiology.

bioRxiv · Aug 14, 2023 · PreprintCell Biology

Severe dysregulation of TNF expression leads to multiple inflammatory diseases and embryonic death

P. Bouillet, E. Clayer, D. Dalseno, A. J. Kueh, D. Lacey, M. Tsai, E. Carr, V. Wimmer

The paper identifies a new regulatory element in the Tnf 3UTR that cooperates with existing elements to downregulate TNF expression and prevent autoimmune diseases, and shows excessive TNF causes embryonic death.

bioRxiv · May 28, 2020 · PreprintImmunology

BCL-XL is essential for the protection from secondary anemia caused by radiation-induced fatal kidney damage

K. Brinkmann, P. Waring, S. Glaser, V. Wimmer, D. Nhu, L. Whitehead, A. R. Delbridge, G. Lessene, M. Herold, G. L. Kelly, S. Grabow, A. Strasser

The paper shows that BCL-XL protects adult kidneys from radiation-induced damage, leading to secondary anemia, and highlights its importance in cancer therapy combinations.

bioRxiv · Apr 28, 2020 · PreprintPharmacology & Toxicology