Author

K. Brinkmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Strasser· 4 shared M. Herold· 2 shared M. J. Herold· 2 shared V. Wimmer· 2 shared A. J. Kueh· 1 shared A. Janic· 1 shared A. K. Voss· 1 shared A. R. Delbridge· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCell Biology

A. Strasser

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice

A. Janic, A. Strasser, M. Herold, M. S. Brennan, G. Healey, L. Gangoda, K. Brinkmann

The paper shows that combined absence of TRP53 target genes ZMAT3, PUMA, and p21 in mice leads to a higher incidence of cancer, with different tumor types depending on which genes are missing.

Cell Death & Differentiation · Dec 18, 2023Peer-reviewedCancer Biology

Relative importance of MCL-1's Anti-Apoptotic versus Non-Apoptotic Functions in vivo

K. Brinkmann, K. McArthur, A. Tee, A. J. Kueh, S. Malelang, V. Wimmer, L. Gibson, C. L. Rowe, P. Arandjelovic, G. Dewson, T. Putoczki, P. Bouillet, N. Fu, T. Thomas, M. J. Herold, , A. Strasser

This study replaces MCL-1 with other anti-apoptotic proteins in mice to determine the relative importance of MCL-1's anti-apoptotic versus non-apoptotic functions in development and physiology.

bioRxiv · Aug 14, 2023 · PreprintCell Biology

BCL-XL is essential for the protection from secondary anemia caused by radiation-induced fatal kidney damage

K. Brinkmann, P. Waring, S. Glaser, V. Wimmer, D. Nhu, L. Whitehead, A. R. Delbridge, G. Lessene, M. Herold, G. L. Kelly, S. Grabow, A. Strasser

The paper shows that BCL-XL protects adult kidneys from radiation-induced damage, leading to secondary anemia, and highlights its importance in cancer therapy combinations.

bioRxiv · Apr 28, 2020 · PreprintPharmacology & Toxicology

miR17~92 is essential for the survival of hematopoietic stem and progenitor cells by restraining pro-apoptotic BIM

K. Brinkmann, C. Hyland, C. A. de Graaf, A. Strasser, W. S. Alexander, M. J. Herold

This study shows that miR17~92 is essential for hematopoietic stem and progenitor cell survival by suppressing the pro-apoptotic protein BIM.

bioRxiv · Jun 8, 2018Cell Biology