Author

D. Orringer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Taher· 1 shared C. Gao· 1 shared D. Hambardzumyan· 1 shared F. Nunez· 1 shared G. Nunez· 1 shared J. Heth· 1 shared J. Liu· 1 shared J. Welch· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Taher

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1 paper

Recent·Most cited

G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT

M. S. Alghamri, R. Avvari, R. Thalla, N. Kamran, L. Zhang, M. Ventosa, A. Taher, S. Faisal, F. Nunez, M. Garcia-Fabiani, S. Haase, S. Carney, D. Orringer, S. Hervey-Jumper, J. Heth, , M. G. Castro

The paper shows that mIDH1 glioma stem cells secrete G-CSF, which reprograms myeloid cells to become non-immunosuppressive, altering the tumor microenvironment.

bioRxiv · Jul 22, 2020 · PreprintCancer Biology