Author

M. Ventosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

M. G. Castro· 2 shared A. Comba· 1 shared A. E. Argento· 1 shared A. Taher· 1 shared C. Gao· 1 shared D. Hambardzumyan· 1 shared D. Orringer· 1 shared D. Zamler· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

M. G. Castro

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2 papers

Recent·Most cited

G-CSF SECRETED BY EPIGENETICALLY REPROGRAMMED MUTANT IDH1 GLIOMA STEM CELLS REVERSES THE MYELOID CELLS'-MEDIATED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT

M. S. Alghamri, R. Avvari, R. Thalla, N. Kamran, L. Zhang, M. Ventosa, A. Taher, S. Faisal, F. Nunez, M. Garcia-Fabiani, S. Haase, S. Carney, D. Orringer, S. Hervey-Jumper, J. Heth, , M. G. Castro

The paper shows that mIDH1 glioma stem cells secrete G-CSF, which reprograms myeloid cells to become non-immunosuppressive, altering the tumor microenvironment.

bioRxiv · Jul 22, 2020 · PreprintCancer Biology

FYN tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates anti-glioma immune responses

A. Comba, P. J. Dunn, A. E. Argento, P. Kadiyala, M. Ventosa, P. Patel, D. Zamler, F. J. Nunez, L. Zhao, M. G. Castro, P. R. Lowenstein

This study shows that FYN tyrosine kinase in glioma cells suppresses anti-glioma immune responses, and its inhibition reduces tumor growth and improves survival in immune-competent models.

bioRxiv · Dec 17, 2019Cancer Biology