MicrobiologyApplied and Environmental MicrobiologyPeer-reviewed
Adaptive laboratory evolution and reverse engineering of single-vitamin prototrophies in Saccharomyces cerevisiae.
T. Perli, D. P. I. Moonen, M. van den Broek…·J.-M. G. Daran
This paper shows that adaptive laboratory evolution can enable Saccharomyces cerevisiae to grow without individual B-vitamins, and identifies key mutations responsible for this trait.
DOI 10.1128/aem.00388-20