J. T. Pronk

This study shows that co-cultivating two engineered yeast strains reduces byproducts and improves ethanol yield in anaerobic fermentation.

This study optimizes acetate and CO2 reduction pathways in yeast to improve ethanol yields while reducing glycerol production in anaerobic cultures.

This study identifies the high oxygen requirements of Ogataea parapolymorpha in oxygen-limited cultures as due to its inability to reoxidize NADH via glycerol formation, relying instead on aerobic respiration.

This study identifies a squalene-hopene cyclase in Schizosaccharomyces japonicus that enables sterol-independent anaerobic growth by synthesizing hopanoids as sterol surrogates.

This study identifies the absence of a functional sterol-uptake mechanism in K. marxianus as the cause of its oxygen requirement and demonstrates that expressing a squalene-tetrahymanol cyclase enables anaerobic growth.

This paper shows that adaptive laboratory evolution can enable Saccharomyces cerevisiae to grow without individual B-vitamins, and identifies key mutations responsible for this trait.

This study shows that maltotriose consumption in S. pastorianus hybrids arises from regulatory cross-talk between parental sub-genomes, demonstrating heterosis in this industrially relevant trait.

This study examines the physiology of Saccharomyces cerevisiae under near-zero growth rates caused by nitrogen or phosphate limitation, finding stable cultures with high viability and active metabolism.

This study enables maltotriose fermentation in Saccharomyces eubayanus by evolving a chimeric transporter gene through recombination of existing maltose-transporter genes.