Author

D. Paterson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 2 Assay:clinical cohort / trial· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

P. N. A. Harris· 2 shared A. Henderson· 1 shared A. J. Heffernan· 1 shared A. M. Peri· 1 shared A. Trafford· 1 shared B. M. Forde· 1 shared C. Buckley· 1 shared C. Engler· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

P. N. A. Harris

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An optimised method for bacterial nucleic acid extraction from positive blood culture broths for whole genome sequencing, resistance phenotype prediction and downstream molecular applications

M. Bauer, A. M. Peri, L. Luftinger, S. Beisken, H. Bergh, B. M. Forde, C. Buckley, T. Cuddihy, P. Tan, D. Paterson, D. M. Whiley, P. N. A. Harris

This paper optimizes DNA extraction from blood culture broths for whole genome sequencing and resistance prediction, showing high accuracy for common pathogens and potential for rapid diagnostics.

bioRxiv · Jun 30, 2022 · PreprintMicrobiology

Evaluating mono and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the Hollow-Fiber Infection Model

M. L. Avent, K. L. McCarthy, F. Sime, s. naicker, A. J. Heffernan, S. Wallis, D. Paterson, J. A. Roberts

This study evaluates the effectiveness of meropenem and amikacin as monotherapy and combination therapy against Pseudomonas aeruginosa isolates using a hollow-fiber infection model, finding improved bacterial killing with combination therapy.

bioRxiv · Dec 23, 2021Pharmacology & Toxicology

Mechanistic insights into ventricular arrhythmogenesis of hydroxychloroquine and azithromycin for the treatment of COVID-19

G. Wang, X. Tian, C.-J. Lu, H. Flores, P. Maj, K. Zhang, Y. Niu, L. Wang, Y. Du, X. Ji, Y. Xu, A. Trafford, D. Li, N. Herring, D. Paterson, , G. Hao

This study investigates the cardiac electrophysiological effects of hydroxychloroquine and azithromycin, showing they prolong QT intervals and increase arrhythmia risk when combined.

bioRxiv · May 21, 2020Pharmacology & Toxicology

Prospective evaluation of beta-lactamase detection in penicillin susceptible Staphylococcus aureus by interpretation of the penicillin disc edge

A. Henderson, D. Whiley, F. Francis, C. Engler, M. Glover, J. Douglas, L. Gore, P. N. A. Harris, D. Paterson, G. R. Nimmo, R. Norton

The study evaluates the penicillin disc edge interpretation method for detecting blaZ in penicillin susceptible Staphylococcus aureus isolates, finding high sensitivity and specificity compared to PCR.

bioRxiv · Sep 26, 2019 · PreprintMicrobiology