Mechanistic insights into ventricular arrhythmogenesis of hydroxychloroquine and azithromycin for the treatment of COVID-19
G. Wang, X. Tian, C.-J. Lu, H. Flores, P. Maj, K. Zhang, Y. Niu, L. Wang, Y. Du, X. Ji, Y. Xu, A. Trafford, D. Li, N. Herring, D. Paterson, , G. Hao
This study investigates the cardiac electrophysiological effects of hydroxychloroquine and azithromycin, showing they prolong QT intervals and increase arrhythmia risk when combined.
bioRxiv · May 21, 2020Pharmacology & Toxicology