Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s Disease
C. Grinyan-Ferre, S. Codony, E. Pujol, J. Yang, R. Leiva, C. Escolano, D. Puigoriol-Illamola, J. Companys-Alemany, R. Corpas, C. Sanfeliu, M. I. Loza, J. M. Brea, C. Morisseau, B. D. Hammock, S. Vazquez, , C. Galdeano
This study investigates the therapeutic potential of sEH inhibition in Alzheimer’s Disease, showing reduced cognitive impairment, tau pathology, and amyloid plaques in animal models.
bioRxiv · Apr 10, 2019Pharmacology & Toxicology