Molecular BiologybioRxivPreprint
RL-118 and 11β-HSD1 target engagement through TAPS assay: behaviour and molecular analysis
Dolors Puigoriol‐Illamola, J. Companys-Alemany, Natalie Z M Homer…·Mercè Pallàs
This study investigates the effects of RL-118, an 11β-HSD1 inhibitor, on cognitive and molecular changes induced by chronic mild stress in SAMP8 mice, showing restoration of stress-induced impairments.
DOI 10.1101/2020.10.27.356881