Author

B. D. Hammock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Morisseau· 2 shared J. Yang· 2 shared A. Takamura· 1 shared C. Escolano· 1 shared C. Galdeano· 1 shared C. Grinyan-Ferre· 1 shared C. Sanfeliu· 1 shared D. Li· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

C. Morisseau

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Author profile →

2 papers

Recent·Most cited

PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction

Y. Wang, C. Morisseau, A. Takamura, D. Wan, D. Li, S. Sidoli, J. Yang, D. W. Wolan, B. D. Hammock, S. Kitamura

This paper develops first-in-class PROTACs that selectively degrade cytosolic sEH, reducing ER stress more effectively than sEH inhibitors.

bioRxiv · Jan 20, 2022 · PreprintBiochemistry

Pharmacological inhibition of soluble epoxide hydrolase as a new therapy for Alzheimer’s Disease

C. Grinyan-Ferre, S. Codony, E. Pujol, J. Yang, R. Leiva, C. Escolano, D. Puigoriol-Illamola, J. Companys-Alemany, R. Corpas, C. Sanfeliu, M. I. Loza, J. M. Brea, C. Morisseau, B. D. Hammock, S. Vazquez, , C. Galdeano

This study investigates the therapeutic potential of sEH inhibition in Alzheimer’s Disease, showing reduced cognitive impairment, tau pathology, and amyloid plaques in animal models.

bioRxiv · Apr 10, 2019Pharmacology & Toxicology