Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma
A. R. Iyer, A. Gurumurthy, R. Kodgule, A. R. Aguilar, T. Saari, A. Ramzan, D. Rausch, J. Gupta, C. N. Hall, J. S. Runge, M. B. Weiss, M. Rahmat, R. Anyoha, C. P. Fulco, I. M. Ghobrial, , R. J. Ryan
The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.
bioRxiv · May 2, 2023 · PreprintCancer Biology