Author

R. Kodgule

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. R. Aguilar· 2 shared C. N. Hall· 2 shared I. M. Ghobrial· 2 shared J. Gupta· 2 shared M. P. Cieslik· 2 shared M. Rahmat· 2 shared T. Saari· 2 shared A. C. Monovich· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

A. R. Aguilar

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3 papers

Recent·Most cited

Novel mechanism of MYC deregulation in Multiple Myeloma

M. Rahmat, K. Clement, J.-B. Alberge, R. Sklavenitis-Pistofidis, R. Kodgule, C. Fulco, D. Heilpern-Mallory, K. Nilsson, D. Dorfman, J. Engreitz, G. Getz, L. Pinello, R. Ryan, I. M. Ghobrial

The paper identifies a new epigenetic mechanism of MYC deregulation in multiple myeloma through enhancer accessibility and transcription factor binding, independent of translocations or amplifications.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

A. R. Iyer, A. Gurumurthy, R. Kodgule, A. R. Aguilar, T. Saari, A. Ramzan, D. Rausch, J. Gupta, C. N. Hall, J. S. Runge, M. B. Weiss, M. Rahmat, R. Anyoha, C. P. Fulco, I. M. Ghobrial, , R. J. Ryan

The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.

bioRxiv · May 2, 2023 · PreprintCancer Biology

ETV6 Deficiency and Microsatellite Enhancers Drive Transcriptional Dysregulation in B-Lymphoblastic Leukemia

R. Kodgule, J. W. Goldman, A. C. Monovich, T. Saari, C. N. Hall, N. Rajesh, J. Gupta, A. R. Aguilar, N. A. Brown, M. Y. Chiang, M. P. Cieslik, R. J. H. Ryan

This study identifies GGAA microsatellite enhancers as drivers of transcriptional dysregulation in ETV6-deficient B-ALL, revealing a novel epigenetic mechanism and limitations of animal models.

bioRxiv · Sep 20, 2022Cancer Biology