Author

J. Gupta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. R. Aguilar· 2 shared C. N. Hall· 2 shared M. P. Cieslik· 2 shared R. Kodgule· 2 shared T. Saari· 2 shared A. C. Monovich· 1 shared A. Gurumurthy· 1 shared A. Han· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

A. R. Aguilar

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Author profile →

4 papers

Recent·Most cited

Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300

A. Nagarajan, K. Scoggin, J. Gupta, M. Aminian, L. G. Adams, M. Kirby, D. threadgill, H. L. Andrews-Polymenis

The paper infects genetically diverse Collaborative Cross mice with MRSA to identify host genetic factors influencing infection outcomes, finding distinct phenotypes and candidate genes associated with susceptibility, tolerance, and resistance.

bioRxiv · Jul 12, 2023 · PreprintMicrobiology

Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

A. R. Iyer, A. Gurumurthy, R. Kodgule, A. R. Aguilar, T. Saari, A. Ramzan, D. Rausch, J. Gupta, C. N. Hall, J. S. Runge, M. B. Weiss, M. Rahmat, R. Anyoha, C. P. Fulco, I. M. Ghobrial, , R. J. Ryan

The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.

bioRxiv · May 2, 2023 · PreprintCancer Biology

ETV6 Deficiency and Microsatellite Enhancers Drive Transcriptional Dysregulation in B-Lymphoblastic Leukemia

R. Kodgule, J. W. Goldman, A. C. Monovich, T. Saari, C. N. Hall, N. Rajesh, J. Gupta, A. R. Aguilar, N. A. Brown, M. Y. Chiang, M. P. Cieslik, R. J. H. Ryan

This study identifies GGAA microsatellite enhancers as drivers of transcriptional dysregulation in ETV6-deficient B-ALL, revealing a novel epigenetic mechanism and limitations of animal models.

bioRxiv · Sep 20, 2022Cancer Biology

Sub-second heat inactivation of coronavirus

Y. Jiang, H. Zhang, J. A. Wippold, J. Gupta, J. Dai, P. de Figueiredo, J. L. Leibowitz, A. Han

This paper develops a system to measure sub-second heat inactivation of coronavirus and identifies conditions achieving >5 Log10 viral titer reduction.

bioRxiv · Oct 5, 2020 · PreprintBioengineering