Author

M. Rahmat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

I. M. Ghobrial· 3 shared G. Getz· 2 shared R. Kodgule· 2 shared R. Sklavenitis-Pistofidis· 2 shared A. Dutta· 1 shared A. Gurumurthy· 1 shared A. J. Dunford· 1 shared A. R. Aguilar· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

I. M. Ghobrial

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3 papers

Recent·Most cited

Novel mechanism of MYC deregulation in Multiple Myeloma

M. Rahmat, K. Clement, J.-B. Alberge, R. Sklavenitis-Pistofidis, R. Kodgule, C. Fulco, D. Heilpern-Mallory, K. Nilsson, D. Dorfman, J. Engreitz, G. Getz, L. Pinello, R. Ryan, I. M. Ghobrial

The paper identifies a new epigenetic mechanism of MYC deregulation in multiple myeloma through enhancer accessibility and transcription factor binding, independent of translocations or amplifications.

bioRxiv · May 19, 2023 · PreprintCancer Biology

Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

A. R. Iyer, A. Gurumurthy, R. Kodgule, A. R. Aguilar, T. Saari, A. Ramzan, D. Rausch, J. Gupta, C. N. Hall, J. S. Runge, M. B. Weiss, M. Rahmat, R. Anyoha, C. P. Fulco, I. M. Ghobrial, , R. J. Ryan

The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.

bioRxiv · May 2, 2023 · PreprintCancer Biology

Genetic Subtypes of Smoldering Multiple Myeloma are associated with Distinct Pathogenic Phenotypes and Clinical Outcomes

M. Bustoros, S. Anand, R. Sklavenitis-Pistofidis, R. Redd, E. M. Boyle, B. Zhitomirsky, A. J. Dunford, Y.-T. Tai, S. J. Chavda, C. Boehner, C. J. Neuse, M. Rahmat, A. Dutta, T. Casneuf, R. Verona, , I. M. Ghobrial

This study identifies six genetic subtypes of smoldering multiple myeloma associated with distinct clinical outcomes and progression risks.

bioRxiv · Dec 10, 2021Cancer Biology