Author

C. N. Hall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. R. Aguilar· 2 shared J. Gupta· 2 shared M. P. Cieslik· 2 shared R. Kodgule· 2 shared T. Saari· 2 shared A. C. Monovich· 1 shared A. Gurumurthy· 1 shared A. R. Iyer· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

A. R. Aguilar

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Author profile →

4 papers

Recent·Most cited

Spheroid architecture strongly induces miR-221/222 expression and promotes oxidative phosphorylation and survival of mobile tumor cells through a mechanism that includes restriction of miR-9 expression

A. S. Ward, C. N. Hall, M. O. Tree, D. S. Kohtz

This study shows that spheroid architecture increases miR-221/222 expression and OXPHOS activity in ovarian cancer cells, enhancing their survival in nutrient-poor environments.

bioRxiv · Aug 22, 2023 · PreprintCancer Biology

Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma

A. R. Iyer, A. Gurumurthy, R. Kodgule, A. R. Aguilar, T. Saari, A. Ramzan, D. Rausch, J. Gupta, C. N. Hall, J. S. Runge, M. B. Weiss, M. Rahmat, R. Anyoha, C. P. Fulco, I. M. Ghobrial, , R. J. Ryan

The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.

bioRxiv · May 2, 2023 · PreprintCancer Biology

ETV6 Deficiency and Microsatellite Enhancers Drive Transcriptional Dysregulation in B-Lymphoblastic Leukemia

R. Kodgule, J. W. Goldman, A. C. Monovich, T. Saari, C. N. Hall, N. Rajesh, J. Gupta, A. R. Aguilar, N. A. Brown, M. Y. Chiang, M. P. Cieslik, R. J. H. Ryan

This study identifies GGAA microsatellite enhancers as drivers of transcriptional dysregulation in ETV6-deficient B-ALL, revealing a novel epigenetic mechanism and limitations of animal models.

bioRxiv · Sep 20, 2022Cancer Biology

SARS-CoV-2 variants of concern Alpha, Beta, Gamma and Delta have extended ACE2 receptor host-ranges

N. Thakur, G. Gallo, J. Newman, T. P. Peacock, L. Biasetti, C. N. Hall, E. Wright, W. Barclay, D. Bailey

The paper examines whether SARS-CoV-2 variants Alpha, Beta, Gamma, and Delta have altered ACE2 receptor usage across different mammalian species, finding that N501Y and E484K substitutions in the Spike RBD expand their host range.

bioRxiv · Nov 23, 2021Microbiology