Author

D. Roame

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. Thomas· 2 shared L. Pongor· 2 shared N. Takahashi· 2 shared P. Carter· 2 shared P. Desai· 2 shared S. Nichols· 2 shared W. D. Figg· 2 shared A. Grinshpun· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

A. Thomas

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2 papers

Recent·Most cited

Genomic alterations and transcriptional phenotypes in circulating tumor DNA and matched metastatic tumor

N. Takahashi, L. Pongor, S. P. Agrawal, M. Shtumpf, V. N. Rajapakse, A. Shafiei, C. W. Schultz, S. Kim, D. Roame, P. Carter, R. Vilimas, S. Nichols, P. Desai, W. D. Figg, M. Bagheri, , A. Thomas

This study compares genomic alterations and transcriptional phenotypes in circulating tumor DNA and matched metastatic tumors in SCLC patients, finding cfDNA reflects tumor mutations, identifies resistance mechanisms, and tracks tumor evolution.

bioRxiv · Jun 2, 2024 · PreprintCancer Biology

Subtyping of Small Cell Lung Cancer using plasma cell-free nucleosomes

G. Fialkoff, N. Takahashi, I. Sharkia, J. Gutin, N. Hermoni, R. Kumar, L. Pongor, S. Nichols, L. Sciuto, C. Graham, P. Desai, M. Nirula, P. Suresh, M. Abel, R. Elmeskini, , A. Thomas

This study uses cfChIP-seq on plasma samples to subtype SCLC based on epigenetic states, linking plasma nucleosome data to tumor transcriptomes and developing a classifier for lineage-defining transcription factors.

bioRxiv · Jun 24, 2022 · PreprintCancer Biology