A. Shafiei

Ambient Temperature Bacterial Large Ribosomal Subunit Structure Enabled by Serial Femtosecond X-ray Crystallography

This study determines the structure of the 50S ribosomal subunit from Thermus thermophilus at ambient temperature using serial femtosecond X-ray crystallography, revealing new dynamics and antibiotic binding sites.

Ambient temperature crystal structure of Escherichia coli CyaY protein displays alternate conformation

The paper presents the first ambient temperature crystal structure of Escherichia coli CyaY, revealing an alternate conformation and highlighting temperature's impact on protein structure.

Rapid and Efficient Ambient Temperature X-ray Crystal Structure Determination at Turkish Light Source

The paper introduces a plate-reader module for rapid ambient temperature X-ray crystallography at a home source and reports the first lysozyme structure determined at Turkish DeLight.

Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source: Turkish DeLight

The paper describes the setup and application of a new X-ray crystallography facility in Turkey for structural analysis of biomacromolecules using lysozyme as a model.

Structural insight into host plasma membrane association and assembly of HIV-1 Matrix protein

This study presents crystal structures of HIV-1 MA domain bound to IP6, revealing its binding mode and interaction with PIP2, providing insights into virion assembly.

Near-Physiological-Temperature Serial Femtosecond X-ray Crystallography Reveals Novel Conformations of SARS-CoV-2 Main Protease Active Site for Improved Drug Repurposing

The paper determines two apo structures of SARS-CoV-2 main protease at near-physiological temperature using SFX and uses molecular simulations to analyze inhibitor binding for drug repurposing.