Author

D. Ruddy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bric· 1 shared A. Buhles· 1 shared A. Li· 1 shared A. Vattay· 1 shared A. Weiss· 1 shared C. D. Adair· 1 shared C. Luu· 1 shared C. Russ· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Bric

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Therapeutic assessment of targeting ASNS combined with L-Asparaginase treatment in solid tumors and investigation of resistance mechanisms

V. Apfel, D. Begue, V. Cordo, L. Holzer, L. Martinuzzi, A. Buhles, G. Kerr, I. Barbosa, U. Naumann, M. Piquet, D. Ruddy, A. Weiss, S. Ferretti, R. Almeida, D. Bonenfant, , G. G. Galli

This study assesses targeting ASNS with L-Asparaginase in solid tumors, identifies resistance mechanisms, and proposes therapeutic combinations.

bioRxiv · Sep 8, 2020Cancer Biology

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling

Z. Jagani, G. Chenail, K. Xiang, G. Bushold, H.-E. C. Bhang, A. Li, G. Elliott, J. Zhu, A. Vattay, T. Gilbert, A. Bric, R. Kikkawa, V. Dubost, R. Terranova, J. Cantwell, , Haas

This study validates novel BRM/BRG1 ATPase inhibitors as chemical probes for SWI/SNF chromatin remodeling and shows their therapeutic potential in BRG1-mut lung cancers.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology