Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from human induced pluripotent stem cells
N. Tamaoki, S. Siebert, T. Maeda, N.-H. Ha, M. L. Good, Y. Huang, S. K. Vodnala, J. J. H. Mora, U. Naoya, J. F. Tisdale, C. L. Sweeney, U. Choi, J. Brault, S. Koontz, H. L. Malech, , R. Vizcardo
This study develops yolk sac-like organoids from hiPSCs to generate multipotent hematopoietic progenitor cells in a scalable and xeno-free system.
bioRxiv · Apr 25, 2021Cell Biology