SMARCD1 is a "Goldilocks" metastasis modifier
C. R. Ross, L.-Y. Gong, L. M. Jenkins, N.-h. Ha, M. Majocha, K. Hunter
The paper identifies Smarcd1 as a 'Goldilocks' metastasis modifier gene, showing that both high and low expression correlate with better clinical outcomes, while intermediate expression worsens survival in breast cancer.
bioRxiv · Jan 24, 2024Cancer Biology