Author

D. T. Humphreys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Husain· 1 shared A. Lin· 1 shared A. M. Nicks· 1 shared A. Y. Chan· 1 shared E. Giannoulatou· 1 shared M. A. Baker· 1 shared M. Li· 1 shared M. Tsang· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Husain

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2 papers

Recent·Most cited

Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts

A. M. Nicks, S. R. Holman, A. Y. Chan, M. Tsang, P. E. Young, D. T. Humphreys, N. Naqvi, A. Husain, M. Li, N. J. Smith, S. E. Iismaa, R. M. Graham

This paper develops a standardized method to isolate and purify high-quality cardiomyocytes from murine hearts of all postnatal ages, revealing sex-specific genes and preserving cell morphology.

bioRxiv · Sep 30, 2021Cell Biology

The rapid evolution of flagellar ion-selectivity in experimental populations of E. coli

P. Ridone, T. Ishida, A. Lin, D. T. Humphreys, E. Giannoulatou, Y. Sowa, M. A. Baker

The paper shows that E. coli can rapidly revert a CRISPR-induced Na+-powered flagellar motor to H+-powered by evolving new mutations, revealing adaptability and modularity of the motor complex.

bioRxiv · Jan 26, 2021Microbiology