Author

Y. Sowa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:E. coli· 3 Research Focus:cell type annotation· 2 Organism:bacteria (other)· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

T. Ishida· 4 shared M. A. Baker· 3 shared P. Ridone· 2 shared R. Ito· 2 shared A. Kitao· 1 shared A. Lin· 1 shared B. J. Buckley· 1 shared D. T. Humphreys· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

T. Ishida

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Novel amiloride derivatives that inhibit bacterial motility across multiple strains and stator types

M. I. Islam, J. Bae, T. Ishida, P. Ridone, J. Lin, M. J. Kelso, Y. Sowa, B. J. Buckley, M. A. Baker

This paper identifies two amiloride derivatives that inhibit bacterial motility across multiple strains and stator types, including both Na+ and H+ powered motors.

bioRxiv · Apr 13, 2021Microbiology

The rapid evolution of flagellar ion-selectivity in experimental populations of E. coli

P. Ridone, T. Ishida, A. Lin, D. T. Humphreys, E. Giannoulatou, Y. Sowa, M. A. Baker

The paper shows that E. coli can rapidly revert a CRISPR-induced Na+-powered flagellar motor to H+-powered by evolving new mutations, revealing adaptability and modularity of the motor complex.

bioRxiv · Jan 26, 2021Microbiology

Injectable prevascularized mature adipose tissues (iPAT) to achieve long-term survival in soft tissues regeneration

F. Louis, Y. Sowa, S. Irie, S. Kitano, O. Mazda, M. Matsusaki

The paper develops injectable prevascularized adipose tissues (iPAT) that show improved cell survival and volume maintenance in mice after 3 months.

bioRxiv · Dec 7, 2020Bioengineering

Distinct chemotactic behavior in the original Escherichia coli K-12 depending on forward-and-backward swimming, not on run-tumble movements

Y. Kinosita, T. Ishida, M. Yoshida, R. Ito, Y. V. Morimoto, K. Goto, R. M. Berry, T. Nishizaka, Y. Sowa

This study identifies a novel swimming behavior in E. coli K-12 strain ATCC10798, driven by forward-and-backward motion rather than run-tumble, linked to a mutation in FliC.

bioRxiv · Feb 13, 2020Microbiology

High pressure inhibits signaling protein binding to the flagellar motor and bacterial chemotaxis through enhanced hydration

H. Hata, Y. Nishihara, M. Nishiyama, Y. Sowa, I. Kawagishi, A. Kitao

This study investigates how high pressure affects CheYp-FliM binding in E. coli chemotaxis using molecular dynamics and microscopy, finding that pressure weakens binding by ~10 kcal/mol and inhibits motor reversal.

bioRxiv · Sep 9, 2019Biophysics

Sodium-powered stators of the bacterial flagellar motor can generate torque in the presence of phenamil with mutations near the peptidoglycan-binding region.

T. Ishida, R. Ito, J. Clark, N. J. Matzke, Y. Sowa, M. A. Baker

The paper identifies mutations in the sodium-powered bacterial flagellar motor stator PotB that confer resistance to phenamil, showing that mutations near the peptidoglycan-binding region enable motor function in the presence of the inhibitor.

bioRxiv · Mar 18, 2019Microbiology