Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam
T. T. Lam, D. Toffaletti, J. Tenor, C. Giamberardino, G. Sempowski, Y. Asfaw, T. H. Phan, A. V. Duong, T. M. Nguyen, L. P. H. Nguyen, C. T. H. Tran, P. M. Ashton, J. Beardsley, C. V. V. Nguyen, G. E. Thwaites, , J. N. Day
This study compares the virulence of Cryptococcus neoformans ST5 and non-ST5 isolates in HIV-infected and uninfected patients in Vietnam, finding ST5 isolates show greater variability and initial inflammatory response but lower fungal burden in mice.
bioRxiv · Feb 19, 2020Microbiology