Polo-like kinase 4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly
J. M. Ryniawec, D. W. Buster, L. K. Slevin, C. J. Boese, A. Amoiroglou, S. Dean, K. C. Slep, G. C. Rogers
This study shows that Plk4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly, as dimer mutants remain functional through concentration-dependent aggregation.
bioRxiv · Nov 15, 2021 · PreprintCell Biology