Author
K. C. Slep
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2017-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links7 papers
Recent·Most cited
Crystal structure of the Arabidopsis SPIRAL2 C-terminal domain reveals a p80-Katanin-like domain
D. L. Bolhuis, R. Dixit, K. C. Slep
The paper determines the crystal structure of the Arabidopsis SPIRAL2 C-terminal domain, revealing a p80-Katanin-like fold and highlighting evolutionary convergence with katanin complexes.
bioRxiv · Dec 28, 2022 · PreprintBiophysics
Polo-like kinase 4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly
J. M. Ryniawec, D. W. Buster, L. K. Slevin, C. J. Boese, A. Amoiroglou, S. Dean, K. C. Slep, G. C. Rogers
This study shows that Plk4 homodimerization is not required for catalytic activation, autodestruction, or centriole assembly, as dimer mutants remain functional through concentration-dependent aggregation.
bioRxiv · Nov 15, 2021 · PreprintCell Biology
Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis
K. Perez-Vale, K. Yow, A. Byrnes, T. Finegan, K. C. Slep, M. Peifer
The paper investigates how multivalent interactions contribute to the robustness of adherens junction-cytoskeletal linkage during Drosophila morphogenesis.
bioRxiv · May 4, 2021Cell Biology
Structures of TOG1 and TOG2 From the Human Microtubule Dynamics Regulator CLASP1
The paper presents the x-ray crystal structures of human CLASP1 TOG1 and TOG2, revealing structural differences from XMAP215 TOG domains and insights into their roles in microtubule dynamics.
bioRxiv · Nov 26, 2018Biophysics
An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly
T. A. McLamarrah, D. W. Buster, B. J. Galletta, C. J. Boese, J. M. Ryniawec, N. A. Hollingsworth, A. E. Byrnes, C. W. Brownlee, K. C. Slep, N. M. Rusan, G. C. Rogers
The paper shows that Plk4 phosphorylates Ana2 in an ordered pattern, essential for centriole assembly and integrity.
bioRxiv · Dec 28, 2017Cell Biology
Control of microtubule dynamics using an optogenetic microtubule plus end-F-actin cross-linker
R. C. Adikes, R. A. Hallett, B. F. Saway, B. Kuhlman, K. C. Slep
This paper introduces an optogenetic tool, SxIP-iLID, to control microtubule dynamics by cross-linking MT plus ends with F-actin, revealing effects on MT growth and lamellar exclusion zones.
bioRxiv · May 26, 2017Cell Biology