Dual targeting of KDM1A and antioxidants is an effective anticancer strategy
S. Mudambi, M. E. Fitzgerald, D. Washington, P. Pera, W. J. HUSS, G. J. Paragh
This study shows that inhibiting KDM1A increases cellular ROS and sensitivity to oxidative stress, which can be mitigated by antioxidants, suggesting dual targeting of KDM1A and antioxidants as a potential anticancer strategy.
bioRxiv · Jun 12, 2024 · PreprintCancer Biology