BiophysicsbioRxiv
Mechanosensing through direct binding of tensed F-actin by LIM domains
X. Sun, D. Y. Z. Phua, L. Axiotakis…·G. M. Alushin
The paper identifies LIM domains' direct binding to tensed F-actin as a mechanosensing mechanism, showing force-dependent sequestration affects nuclear localization.
DOI 10.1016/j.devcel.2020.09.022