A marker-free co-selection strategy for high efficiency human genome engineering
Daniel Agudelo, Alexis Duringer, Lusiné Bozoyan, Caroline Huard, Sophie Carter, Jérémy Loehr, Dafni Synodinou, Mathieu Drouin, Jayme Salsman, Graham Dellaire, Josée Laganière, Yannick Doyon
This paper introduces a marker-free co-selection strategy to enhance gene editing efficiency in human cells using CRISPR-Cas9 and Cpf1 systems.
Nature Methods · Apr 17, 2017Peer-reviewedMolecular Biology