Author
Centre hospitalier universitaire de QuébecORCID 0000-0002-8794-4279Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Sébastien Levesque, Diana Mayorga, Jean-Philippe Fiset…·Yannick Doyon
This paper introduces a coselection strategy for prime editing in human cells using the Na+/K+ ATPase to enable efficient multiallelic editing and reduce the need for pegRNA optimization.
Daniel Agudelo, Sophie Carter, Minja Velimirovic…·Yannick Doyon
This paper engineers CRISPR-Cas9 variants from Streptococcus thermophilus to target diverse A-rich PAMs, enabling efficient genome editing in mice.
Daniel Agudelo, Alexis Duringer, Lusiné Bozoyan…·Yannick Doyon
This paper introduces a marker-free co-selection strategy to enhance gene editing efficiency in human cells using CRISPR-Cas9 and Cpf1 systems.