Bacteroides fragilis modulates gut microbiome community composition, frontal cortex gene expression, and fecal and frontal cortex metabolites in a mouse model of Alzheimers disease pathologies
Kathryn A Conn, Olivia Schwartz, Shreya Dikshit, Daisy L. Barroso, David Hattan, Chloe Herman, Colin V. Wood, Emily M. Borsom, J. Gregory Caporaso, Allegra T. Aron, Emily K. Cope
This study shows that Bacteroides fragilis treatment in AD mice alters gut microbiota, reduces neuroinflammation markers, and normalizes brain metabolites.
bioRxiv · May 30, 2026 · PreprintMicrobiology