Author

Dalila Spadoni

Eligo Bioscience (France)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Organism:mouse· 1

Frequent Co-Authors

Andreas K. BrödeliD· 2 shared Chloé Poquet· 2 shared David BikardiD· 2 shared Edith M. HesseliD· 2 shared Fabien J. FucheiD· 2 shared Gautier Prevot· 2 shared Jesús Fernández-RodrígueziD· 2 shared Loïc H. Charpenay· 2 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Andreas K. BrödelORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Treatment of STEC infection via CRISPR-Cas targeted cleavage of the Shiga toxin gene in animal models

Matthieu Galtier, Antonina O. Krawczyk, Fabien J. Fuche, Loïc H. Charpenay, Igor Stzepourginski, Simone Pignotti, Marion Arraou, Rémi Terrasse, Andreas K. Brödel, Chloé Poquet, Gautier Prevot, Dalila Spadoni, Benjamin Buhot, Kristin Munch, Jan Havránek, , Jesús Fernández-Rodríguez

This paper develops a CRISPR-based therapy targeting Shiga toxin genes in STEC infections, showing efficacy in reducing bacterial load and mitigating disease in animal models.

bioRxiv · Feb 28, 2025 · PreprintSynthetic Biology

In situ targeted mutagenesis of gut bacteria

Andreas K. Brödel, Loïc H. Charpenay, Matthieu Galtier, Fabien J. Fuche, Rémi Terrasse, Chloé Poquet, Marion Arraou, Gautier Prevot, Dalila Spadoni, Edith M. Hessel, Jesús Fernández-Rodríguez, Xavier Duportet, David Bikard

This paper develops a method to edit bacterial genes in the gut using a phage-derived particle, achieving high editing efficiency and stable maintenance of modified bacteria.

bioRxiv · Sep 30, 2022 · PreprintSynthetic Biology