Jesús Fernández-Rodríguez

This paper develops a CRISPR-based therapy targeting Shiga toxin genes in STEC infections, showing efficacy in reducing bacterial load and mitigating disease in animal models.

This paper develops a method to edit bacterial genes in the gut using a phage-derived particle, achieving high editing efficiency and stable maintenance of modified bacteria.

This study assesses gene essentiality across diverse E. coli strains and growth conditions, revealing that essentiality varies independently of phylogeny and is influenced by mobile genetic elements.