Author

Dan Spatt

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2

Frequent Co-Authors

Fred WinstoniD· 3 shared James ChuangiD· 3 shared Francheska López-RiveraiD· 2 shared L. Stirling ChurchmaniD· 2 shared Magdalena MurawskaiD· 2 shared Olga ViktorovskayaiD· 2 shared Dhawal S. JainiD· 1 shared Natalia I. Reim· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMolecular Biology

Fred WinstonORCID

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3 papers

Recent·Most cited

Suppressor mutations that make the essential transcription factor Spn1/Iws1 dispensable in Saccharomyces cerevisiae

Francheska López-Rivera, James Chuang, Dan Spatt, Rajaraman Gopalakrishnan, Fred Winston

The paper identifies suppressor mutations in yeast that allow survival without the essential transcription factor Spn1/Iws1 by revealing multiple pathways that compensate for its loss.

Genetics · Aug 17, 2022Peer-reviewedMolecular Biology

Essential histone chaperones collaborate to regulate transcription and chromatin integrity

Olga Viktorovskaya, James Chuang, Dhawal S. Jain, Natalia I. Reim, Francheska López-Rivera, Magdalena Murawska, Dan Spatt, L. Stirling Churchman, Peter J. Park, Fred Winston

This study identifies a network of histone chaperones and elongation factors that coordinate transcriptional accuracy and chromatin structure through their physical interactions.

Genes & Development · May 1, 2021Peer-reviewedGenetics

Spt6 is required for the fidelity of promoter selection

Stephen M. Doris, James Chuang, Olga Viktorovskaya, Magdalena Murawska, Dan Spatt, L. Stirling Churchman, Fred Winston

This study shows Spt6 represses transcription initiation at thousands of intragenic promoters and regulates initiation at most genic promoters, proposing a model of initiation-site competition.

Molecular Cell · Oct 11, 2018Peer-reviewedGenomics