Author

Dana Varghese

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Qian ZhuiD· 2 shared Ahmed M. ElkhananyiD· 1 shared Andrew Davis· 1 shared Angela R. OmilianiD· 1 shared Arun SreekumariD· 1 shared Arundati Rao· 1 shared Badrajee PiyarathnaiD· 1 shared Balasubramanyam KaranamiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Qian ZhuORCID

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2 papers

Recent·Most cited

CancerSTFormer enables multi-scale analysis of spot-resolution spatial transcriptomes and dissects the gene and immune regulatory responses of targeted therapies

Benjamin Strope, Dana Varghese, William Bowie, Stacy Wang, Qian Zhu

CancerSTFormer analyzes spatial transcriptomes to study cancer niches and therapy responses at multiple scales.

bioRxiv · Mar 3, 2026 · PreprintBioinformatics

AADAT-Driven Metabolic Control of Malate and CoQ10 Shapes Immune Evasion in Triple-Negative Breast Cancer

Megha Chatterjee, Franklin Gu, Susmita Samanta, Uttam Rasaily, Sai Manohar Thota, Dana Varghese, YUNPING QIU, Lynette Ewura Esi Fordwuo, Hugo J. Villanueva, Mary Kathryn McKenna, Jun Hyoung Park, Weijie Zhang, Lin Hai Tian, Liqun Yu, Badrajee Piyarathna, , Arun Sreekumar

This paper identifies AADAT as a metabolic immune checkpoint in TNBC that promotes immune evasion by regulating malate and CoQ10, and shows that malate supplementation can reverse immunotherapy resistance.

bioRxiv · Jan 30, 2026 · PreprintCancer Biology