Author

Balasubramanyam Karanam

Mayo ClinicORCID 0000-0002-0782-2539Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ademola Alabi PopoolaiD· 1 shared Ahmed M. ElkhananyiD· 1 shared Andrew Davis· 1 shared Angela R. OmilianiD· 1 shared Arun SreekumariD· 1 shared Arundati Rao· 1 shared Badrajee PiyarathnaiD· 1 shared Benny Abraham KaipparettuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Ademola Alabi PopoolaORCID

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2 papers

Recent·Most cited

AADAT-Driven Metabolic Control of Malate and CoQ10 Shapes Immune Evasion in Triple-Negative Breast Cancer

Megha Chatterjee, Franklin Gu, Susmita Samanta, Uttam Rasaily, Sai Manohar Thota, Dana Varghese, YUNPING QIU, Lynette Ewura Esi Fordwuo, Hugo J. Villanueva, Mary Kathryn McKenna, Jun Hyoung Park, Weijie Zhang, Lin Hai Tian, Liqun Yu, Badrajee Piyarathna, , Arun Sreekumar

This paper identifies AADAT as a metabolic immune checkpoint in TNBC that promotes immune evasion by regulating malate and CoQ10, and shows that malate supplementation can reverse immunotherapy resistance.

bioRxiv · Jan 30, 2026 · PreprintCancer Biology

Whole Exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry

Jason A. White, Ernest T. Kaninjing, Kayode Adebamiji Adeniji, Paul Jibrin, John Oladapo Obafunwa, Chidiebere Ndukwe Ogo, Mohammed Faruk, Ademola Alabi Popoola, Omolara Aminat A. Fatiregun, Olabode Peter Oluwole, Balasubramanyam Karanam, Isra A. Elhussin, Stefan Ambs, Wei Tang, Melissa Boneta Davis, , Clayton Clopton Yates

This study analyzes whole-exome sequencing data from Nigerian prostate cancer tumors to identify germline and somatic variants associated with African ancestry and DNA repair gene mutations.

Cancer Research Communications · Sep 16, 2022Peer-reviewedGenetic & Genomic Medicine