Genetic barcoding of individual cells links cancer evolutionary trajectories and prognostic outcomes
Candice Merle, Ivan Di Terlizzi, Mathilde Huyghe, Danae Welboren, Wenjie Sun, Cécile Conrad, Leïla Perié, Steffen Rulands, Silvia Fré
The paper uses genetic barcoding and single-cell transcriptomics to identify evolutionary trajectories in breast cancer cells, linking them to poor patient survival.
bioRxiv · Dec 2, 2025 · PreprintCancer Biology