Single-cell analysis of severe COVID-19 patients reveals a monocyte-driven inflammatory storm attenuated by Tocilizumab
Chuang Guo, Bin Li, Huan Ma, Xiaofang Wang, Pengfei Cai, Qiaoni Yu, Lin Zhu, Liying Jin, Chen Jiang, Jingwen Fang, Qian Liu, Dandan Zong, Wen Zhang, Yichen Lu, Kun Li, , Kun Qu
The paper uses single-cell analysis to show that Tocilizumab reduces monocyte-driven inflammation in severe COVID-19 but does not fully suppress immune responses.
Nature Communications · Aug 6, 2020Peer-reviewedGenomics