Qiaoni Yu

The paper analyzes single-cell transcriptomes from healthy human endometrium across reproductive stages to understand immune cell dynamics and identify potential biomarkers for reproductive diseases.

The paper identifies two transcription factor clusters regulating NK cell differentiation and highlights FOSL2 and EGR2 as essential for NK cell maturation and function.

The paper uses single-cell analysis to show that Tocilizumab reduces monocyte-driven inflammation in severe COVID-19 but does not fully suppress immune responses.

APEC improves single-cell chromatin accessibility analysis by clustering cells based on accessible regions and integrates with other tools to enhance clustering accuracy and predict gene expression and regulatory elements.