DYT1 mutation alters gut microbiome composition and gut-brain axis dynamics in a mouse model
Jianfeng Xiao, Sazzad Khan, Pradeep K. Shukla, Daniel Johnson, Mohammad Moshahid Khan
This study shows that DYT1 mutations in mice disrupt gut microbiome composition and gut-brain axis dynamics, linking intestinal dysfunction to motor impairments.
bioRxiv · Dec 17, 2025 · PreprintNeuroscience