Jianfeng Xiao

This study shows that DYT1 mutations in mice disrupt gut microbiome composition and gut-brain axis dynamics, linking intestinal dysfunction to motor impairments.

This study identifies the integrated stress response (ISR) activation and DNA damage-driven immune dysregulation as key drivers of ATO-induced delayed neurotoxicity and cognitive deficits.

This study identifies a cGAS-STING signaling loop driving neuroinflammation and tau pathology in tauopathies, showing its disruption can alleviate disease symptoms.