Bicc1 and dicer regulate left-right patterning through posttranscriptionalcontrol of the Nodal-inhibitor dand5
Markus Maerker, Maike Getwan, Megan E. Dowdle, Jason C. McSheene, Vanessa Gonzalez, José L. Pelliccia, Danielle S. Hamilton, Valeria Yartseva, Charles E. Vejnar, Melanie Tingler, Katsura Minegishi, Philipp Vick, Antonio J. Giráldez, Hiroshi Hamada, Rebecca D. Burdine, , Axel Schweickert
The paper identifies Bicc1 and Dicer1 as regulators of left-right patterning by posttranscriptionally repressing Dand5, a Nodal inhibitor, downstream of flow sensing.
Nature Communications · Sep 16, 2021Peer-reviewedDevelopmental Biology