Katsura Minegishi

The paper shows that immotile cilia in mouse node cells detect mechanical forces from leftward fluid flow, leading to asymmetric molecular responses that break left-right symmetry.

This study evaluates the anti-inflammatory and anti-fibrotic effects of N-163 β-glucan in mdx dystrophic mice, showing reduced fibrosis and inflammation markers.

The paper identifies Bicc1 and Dicer1 as regulators of left-right patterning by posttranscriptionally repressing Dand5, a Nodal inhibitor, downstream of flow sensing.

The paper investigates how fluid flow induces asymmetric Dand5 mRNA decay in the mouse embryo through the Bicc1-Ccr4 RNA degradation complex.

This study shows that SOX2 deficiency in the anterior foregut of mouse embryos leads to the transformation of esophageal and mesenchymal tissues into tracheal and bronchial structures.