Charles E. Vejnar

The paper identifies codon pairs and amino acid pairs as regulators of mRNA stability in zebrafish, showing context-dependent decay mechanisms involving deadenylation and decapping.

The paper introduces NaP-TRAP, a new MPRA method to measure mRNA translation, and uses it to analyze cis-regulatory elements in zebrafish and human cells.

This paper identifies maternal-effect mutants in zebrafish that reveal molecular mechanisms controlling the oocyte-to-egg transition, focusing on yolk globule formation and protein processing.

The paper identifies two micropeptides encoded by lincRNAs that regulate chromatin accessibility in vertebrate-specific neural cells and show their role in brain development.

This study demonstrates the use of SpG and SpRY CRISPR-Cas9 variants in zebrafish and C. elegans for genome editing, showing improved accessibility to previously uneditable sites.

The paper identifies Bicc1 and Dicer1 as regulators of left-right patterning by posttranscriptionally repressing Dand5, a Nodal inhibitor, downstream of flow sensing.

This study shows that Nanog, Pou5f3, and Sox19b work together in a context-dependent way to establish chromatin accessibility and developmental competence in zebrafish embryos.

The paper identifies cis-regulatory elements and trans-factors governing mRNA stability during zebrafish MZT and develops a model to predict mRNA stability.

The paper characterizes mRNA structure dynamics during zebrafish development and identifies ribosome-mediated RNA remodeling and 3-UTR structures as key regulators of gene expression and decay.

This study shows that Brd4 and P300 regulate zygotic genome activation through histone acetylation in zebrafish embryos.

This study shows that LbCpf1 enables efficient homology-directed repair and temperature-controlled genome editing in zebrafish, improving targeted DNA integration.