NREM Oscillations Mediate Synaptic Proteome Remodelling to Support Synapse Stabilisation
Diego del Castillo-Berges, Ana Cazurro‐Gutiérrez, Oriana Zerpa-Rios, Amalia Peñuela-Suarez, Daniel Arco-Alonso, Carla Viñola-Renart, Gisela Espriu-Aguado, Danique C. Zantinge, Thomas Vaissière, Camilo Rojas, Frank Koopmans, Remco V. Klaassen, Benito Domínguez-Velasco, Manuel Álvarez‐Dolado, Julie Seibt, , Àlex Bayés
The paper shows that NREM sleep oscillations drive synaptic proteome remodelling, promoting stabilization and memory consolidation, while altered oscillations in a disorder lead to synaptic weakening.
bioRxiv · Apr 8, 2026 · PreprintNeuroscience