V-type H+ ATPase Activity is Required for Embryonic Dorsal-Ventral Symmetry Breaking
Daphne Schatzberg, Christopher F. Thomas, Patrick Reidy, Sarah E. Hadyniak, Viktoriya Skidanova, Matthew L. Lawton, Luz Dojer, Shweta Kitchloo, Daniel T. Zuch, Cynthia A. Bradham
This study shows that V-ATPase activity is required for DV symmetry breaking in sea urchin embryos, acting upstream of p38 MAPK and Nodal signaling.
bioRxiv · Oct 18, 2021 · PreprintDevelopmental Biology