Daniel T. Zuch

ICAT improves identification of cell states after perturbations in single-cell RNA sequencing by using self-supervised feature weighting and control-guided clustering.

The paper uses calcium-binding fluorochromes to study skeletal patterning dynamics in sea urchin embryos, revealing earlier skeletogenesis onset and delayed triradiate formation in perturbed embryos.

This study shows that V-ATPase activity is required for DV symmetry breaking in sea urchin embryos, acting upstream of p38 MAPK and Nodal signaling.

This study analyzes the transcriptome of Lytechinus variegatus during embryonic and larval development, identifying four temporally distinct phases of gene expression.