Geometrical confinement guides Brachyury self-patterning in embryonic stem cells.
Guillaume Blin, Darren Wisniewski, Catherine Picart, Manuel Théry, Michel Pucéat, Sally Lowell
This study shows that geometric cues can direct the self-patterning of Brachyury-positive cells in embryonic stem cell aggregates without relying on morphogen gradients.
Development · Aug 16, 2018Peer-reviewedDevelopmental Biology