Identification of MAZ as a novel transcription factor regulating erythropoiesis
Darya Deen, Falk Butter, Michelle L. Holland, Vasiliki Samara, Jacqueline A. Sloane-Stanley, Helena Ayyub, Matthias Mann, David Garrick, Douglas Vernimmen
This study identifies MAZ as a novel transcription factor regulating erythropoiesis by binding to the -globin gene promoter and interacting with GATA1-bound enhancers, with knockdown impairing differentiation and genetic variants linked to erythroid traits.
bioRxiv · May 10, 2020 · PreprintMolecular Biology